Friday, August 14, 2009

Overview
Aspergillus fumigatus
A. fumigatus

A. fumigatus causes more infections worldwide than any other mould. Four percent of all patients dying in tertiary care hospitals in Europe have invasive aspergillosis. The fungus causes allergic deseases in asthmatics and patients suffering from cystic fibrosis. Invasive aspergillosis can occur in individuals with cavities caused by tuberculosis or other cystic lung diseases. More information about A. fumigatus can be found at the Aspergillus web site.

Although A. fumigatus is medically important, very little is known about its genetic makeup. Before inception of the whole genome project, less than 60 complete genes had been cloned and published. In contrast, extensive genomic analysis had been carried out on the model fungi Neurospora crassa and Aspergillus nidulans.



http://www.sanger.ac.uk/Projects/A_fumigatus/

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